[HTML][HTML] Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk
… to this and, therefore, it is important to address the underlying … we discuss the role of sex
hormones in the regulation of BAT … role of estrogens on 11β‐HSD1. Whether sex hormones also …
hormones in the regulation of BAT … role of estrogens on 11β‐HSD1. Whether sex hormones also …
Prednisone stimulates white adipocyte browning via β3-AR/p38 MAPK/ERK signaling pathway
S Mukherjee, JW Yun - Life sciences, 2022 - Elsevier
… roles in the control of fat depots, by regulating adipogenesis … -hydroxysteroid dehydrogenase
type 1 (11β-HSD1), which is … in acutely elevating the brown adipose tissue by upregulation …
type 1 (11β-HSD1), which is … in acutely elevating the brown adipose tissue by upregulation …
[HTML][HTML] 11β-HSD As a new target in pharmacotherapy of metabolic diseases
D Kupczyk, R Bilski, M Kozakiewicz… - International journal of …, 2022 - mdpi.com
… For the proper functioning of the body, strict control of their … They play an important regulatory
role in the metabolism of … level of 11β-HSD1 expression in adipose tissue and a higher …
role in the metabolism of … level of 11β-HSD1 expression in adipose tissue and a higher …
Mechanisms in endocrinology: local and systemic effects of glucocorticoids on metabolism: new lessons from animal models
M Swarbrick, H Zhou, M Seibel - European journal of …, 2021 - academic.oup.com
… regulate a remarkable variety of essential functions, including … been shown to influence brown
adipose tissue thermogenesis (… of glucocorticoid actions by 11β-HSD1 in this depot and its …
adipose tissue thermogenesis (… of glucocorticoid actions by 11β-HSD1 in this depot and its …
Distinct response of adipocyte progenitors to glucocorticoids determines visceral obesity via the TEAD1‐miR‐27b‐PRDM16 axis
Y Lv, F Xia, J Yu, Y Sheng, Y Jin, Y Li, G Ding - Obesity, 2023 - Wiley Online Library
… -specific pattern, the regulatory pathways of novel progenitor … strongly promoted the brown
adipogenic potential of both … GC activity within adipose tissue by 11β-HSD1, an amplifier …
adipogenic potential of both … GC activity within adipose tissue by 11β-HSD1, an amplifier …
[HTML][HTML] HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling
M Giroud, FF Tsokanos, G Caratti, S Kotschi, S Khani… - Diabetologia, 2021 - Springer
… (SVF; mSVF) was isolated from brown adipose tissue (BAT), scWAT, and … As adipocyte
function is an important pillar of lipid … an important role very early in the adipocyte differentiation …
function is an important pillar of lipid … an important role very early in the adipocyte differentiation …
Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients
… be an important contributing factor to the clinical features of the latter. … , 11β-HSD1 is also
expressed in brown adipose tissue, bone and brain, where it plays a central role in regulating …
expressed in brown adipose tissue, bone and brain, where it plays a central role in regulating …
Contributions of white and brown adipose tissues to the circadian regulation of energy metabolism
I Heyde, K Begemann, H Oster - Endocrinology, 2021 - academic.oup.com
… hydroxysteroid dehydrogenase type 1 (11β-HSD1), which might … In summary, the circadian
clock is important for adipocyte … As mentioned earlier, it plays a crucial role in the regulation of …
clock is important for adipocyte … As mentioned earlier, it plays a crucial role in the regulation of …
Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess
… in adipose 66 tissue, we propose that HSD11B1 regulates the … that HSD11B1 plays an
essential role in modulating the … 11β-HSD1 inhibition ameliorates metabolic syndrome and …
essential role in modulating the … 11β-HSD1 inhibition ameliorates metabolic syndrome and …
Chronic glucocorticoid exposure causes brown adipose tissue whitening, alters whole‐body glucose metabolism and increases tissue uncoupling protein‐1
… to produce heat and regulate body temperature. Studies examining BAT and its role in
whole-… Future studies investigating excess GCs and BAT uncoupling potential is fundamental to …
whole-… Future studies investigating excess GCs and BAT uncoupling potential is fundamental to …